Adipose Triglyceride Lipase Is Implicated In
نویسندگان
چکیده
STIMULATED INSULIN SECRETION Marie-Line Peyot, Claudiane Guay, Martin G. Latour, Julien Lamontagne, Roxane Lussier, Marco Pineda, Neil B. Ruderman, Guenter Haemmerle, Rudolf Zechner, Érik Joly, S. R. Murthy Madiraju, Vincent Poitout and Marc Prentki Molecular Nutrition Unit and the Montreal Diabetes Research Center, CRCHUM; Departments of Nutrition and Medicine, University of Montreal, Montreal, Quebec H1W 4A4, Canada; Departments of Medicine and Physiology and Biophysics, Boston University School of Medicine and Diabetes Unit, Section of Endocrinology, Boston University School of Medicine and Boston Medical Center, Boston, MA,02118, USA; Inst. of Molecular Biosciences, Karl-Franzens-University, Graz 8010, Austria
منابع مشابه
Comparison of the triglyceride lipase of liver, adipose tissue, and postheparin plasma.
Heparin-released triglyceride lipase from three sources, adipose tissue, liver, and postheparin plasma, was compared. Heparin-released triglyceride lipase from liver differed in several major respects from that in adipose tissue. These differences included response to inhibitors and to high density lipoprotein in the incubation media. Heparin-released triglyceride lipase from liver, when compar...
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Fasted rats injected with actinomycin or fed glucose show increased lipoprotein lipase activity of epididymal adipose tissue. Data from the actinomycin-treated animals showed a direct correlation between the lipoprotein lipase activity and the uptake of lipoprotein triglyceride by the epididymal fat pad in vitro and in vivo. Data from the animals fed glucose confirmed these findings in vitro. T...
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BACKGROUND Dysregulated lipolysis has been implicated in mechanisms of cardiometabolic disease and inflammation in obesity. PURPOSE We sought to examine the effect of bariatric weight loss on adipose tissue lipolytic gene expression and their relationship to systemic metabolic parameters in obese subjects. METHODS/RESULTS We biopsied subcutaneous adipose tissue in 19 obese individuals (BMI ...
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Lipoprotein lipase activity in lipomatous tissue, post-heparin lipoprotein lipase activity in plasma, and the composition and concentration of serum lipoproteins were studied in 15 patients with Multiple Symmetric Lipomatosis (MSL). Extremely elevated lipoprotein lipase activity in adipose tissue was found in MSL patients. Total and hepatic post-heparin plasma lipolytic activity was normal, whi...
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